Katkars - Clinical & Industrial Products

HPV and Cervical Cancer

Cervical cancer is caused in 99.7% of cases (1) by persistent infection with Human Papillomavirus (HPV).

Most HPV infections are transient and fortunately do not induce cervical cancer. However, a small but significant number of HPV infections progress to cervical cancer. The expression of viral oncoproteins E6 and E7 initiate the cervical cancer process by affecting the cell cycle control (2) (see diagram below).

New Generation Test in Cervical Cancer Surveillance

NucliSENS EasyQ HPV is an mRNA-based assay which directly detects active HPV oncogenes (E6 / E7 mRNA) for greater Medical Predictive Value.

Why choose NucliSENS EasyQ™ HPV?

First real-time highly automated CE-IVD assay
Streamlines your workflow
Offers stress-less, state-of-the-art technology
Detects mRNA of E6 and E7
Discriminates between genotypes 16, 18, 31, 33 and 45.
Provides greater Medical Predictive Value

Clear Results for Relevant Decisions
NucliSENS EasyQ HPV uses a new concept to directly detect the expression of the HPV oncogenic (E6 and E7 mRNA) and risk factors discriminate between the more prevalent HPV genotypes in cervical cancer (16, 18, 31, 33 and 45).
By providing clear, relevant results you directly support medical staff in their decision-making process.

Streamline Your Workflow
NucliSENS EasyQ HPV is the first assay to offer you such a high level of automation. Time-to-result can be as short as 4 hours! Simply choose whether sample extraction is performed semi-manually (NucliSENS™ miniMAG™), or fully automated (NucliSENS™ easyMAG™) depending on your workflow.

Real-Time Assay
NucliSENS EasyQ HPV is a CE-IVD, real-time amplification assay for the detection of HPV. For greater result security detection is performed directly in the amplification tubes. Results are also obtained quicker than with other methods.

Stress-less Technology
NucliSENS EasyQ HPV is simply the easiest assay to use currently available on the market: extremely user-friendly interface, limited hands on-time (<1hr for 24 samples), greater traceability.

It is intended for use with cervical specimens collected using a cervical brush and rinsed in a ThinPrep vial containing PreservCyt® solution (Cytyc Corp).

NucliSENS EasyQ HPV
Ref. 290001

References:
1. Walboomers J et al, Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J. Pathol. 1999; 189:12-19.
2. Zur Hausen et al, Papillomaviruses and cancer : from basic studies to clinical application. Nat. Rev. Cancer 2002; 2:342-50.